It should be possible how well it works still needs testing,
I have both duet boards to test out but not had a chance to do it
The firmware needed some additional features but they are working on supporting lasers.
Just take the FabKits smoothie config and copy the details over to their firmware and it should run the FabKit but you will need to do a bit of hacking and tinkering
Any reason you want to run duet over smoothie?